Native Collagen Gel

Collagen called protein of youth, constitutes more than 30% of human protein mass and as much as 70% of skin proteins.

Collagen and elastin in the dermis form a flexible mesh, which gives the dermis its elasticity and firmness, it binds water, lipophilic substances and is also responsible for the condition of connective tissues; that is in fact the condition of the whole body.

Introduction

Natural Fish Collagen is entirely different. It is extracted from fish skin in the form of triple helix (spiral) molecules which are precursors of the collagen fibres. So, in simple words, it would have become collagen fibre but it was captured and extracted from the fish skin at an earlier stage of development and preserved (not processed!) as hydrate. Its molecules maintain their triple helix structure and determine their biological activity in a beauty product. Such helical pro-collagen quickly breaks down into peptides once it touches the skin. These peptides, are transdermal, unlike hydrolysed collagen. Scientifically speaking, we are more entitled to call our flagship product “collagen” than thousands of other distributors whose preparations are made of protein that would be once considered collagen. Our product differs in that it maintains the model structure of collagen and even the inter-spiral and intra-spiral bonds.

Thousands of “collagens” on the market are usually hydrolysates composed of amino acids, which are in our opinion, “post-collagen” proteins. They are not collagen any longer; they merely contain amino acids typical to collagen tissues. Polish collagen extracted directly from fish skin is a tertiary collagen, a stage before it develops into collagen fibrils and then fibres.

This unique Polish method of triple helix collagen extraction and preservation is not used in any other part of the world. However, consumers tend not to know what exactly a hydrolysate is and how and why it is different from a hydrate.

FDA approved.

Native Collagen Gel ingredients (INCI)                 

  • Aqua      
  • Collagen
  • Elastin                     
  • Caprylyl Glycol*
  • Lactic Acid

*Caprylyl glycol is an alcohol derived from caprylic acid, which is naturally found in coconut oil.

Appearance Medicine & Beauty Clinics

For clinic use

Collagen Gel is perfect to enhance benefits of: 

  • (CIT) Collagen Induction Therapy,
  • PRP (Platelet Rich Plasma),
  • Botox, fillers etc.,
  • Microdermabrasion & needling,
  • Dermapen Skin Needling & DermaFrac
  • IPL (Intense Pulsed Light),
  • Laser (after laser to enhance collagen production also to cool down skin and deliver essential peptides helping in regeneration)
  • HIFU (High Intensity Focused Ultrasound),
  • Oxygen Treatment,
  • Photodynamic Therapy,
  • Bio Energy Lift & Rejuvenation
  • Helps in the treatment of dermatitis, eczema, skin irritations, stretch marks
  • Improves skin pigmentation
  • Firms and moisturises the skin
  • helps cut down the downtime/recover after treatments

Native collagen gel protocol for CLINIC use:

  1. Straight after treatment spray skin with 2-3 pumps of Atelowater (or simply water) and spread all over the face, neck and décolletage
  2. Apply 1-2 pumps of the tropocollagen gel and spread all over the face, neck and décolletage.
  3. Massage face, neck and décolletage to the point where all collagen has been absorbed.
  4. Our recommendation. For best results apply Atelomask

Do not use collagen gel in conjunction with cosmetics containing: fruit acids, zinc, ceramides, retinol

Attention!

  • Tight feeling may occur but this is normal.
  • Shake Atelowater vigorously before use to mix ingredients.

***

Plastic Surgery

The scar healing process can vary from patient to patient and it may take up to a year before we see final result, so caring for scar on a daily basis is an important part of its end result. Using tropocollagen gel is the best way to take care of scars and minimize scars appearance. Collagen gel will also help to stimulate the extracellular matrix of the skin to rebuild and strengthen its structure.

Pre- and after surgery (for home treatment)

– Before and after plastic surgery (e.g. breast augmentation, breast lift, breast reconstruction, mastectomy, face lift, neck lift, tummy tuck etc.)

– Used pre-procedure to strengthen the skin structure,

– Used post-procedure to deliver essential peptides helping in healing of the scar, in regeneration, rebuilding, and reconstruction of skin tissues.

And can also be recommended for use in these circumstances:

  • After surgical removing stretch marks,
  • Avoiding skin sagging,
  • Avoiding scarring,
  • Softens and smoothes scars & keloids,
  • Revitalizing treatment of mature skin,
  • Supports the treatment of thermal burns, sunburns, chemical burns, first signs of bedsores,
  • Support for treatment of early detected melanoma,

Native collagen gel helps recover skin immune system and has antiseptic properties.

It’s recommended to ask physician (or nurse) for personal protocol.

Collagen for medical use

primary skin care - use at home

Native collagen gel protocol for HOME use:
For optimal results tropocollagen gel should be applied 2 times a day (best morning and night). It’s recommended to use a face exfoliator once/twice a week to prepare the skin for maximum collagen absorption
1. Cleanse your face with a rough sponge or glove
2. Use 2-3 sprays of Atelowater to dampen skin (or simply water)
3. Apply 1-2 pumps of the gel. Massage a very thin layer of collagen into the skin and rub. A Tight feeling  may occur but this is normal.
4. Apply eye cream and then day cream (MC2 Atelocream) or night cream (Atelomask)
 
 Attention! 
  • Collagen Gel should be stored in in a cool, dry place away from direct sunlight and high humidity in temp up to 37 C. 
  • Do not use collagen in conjunction with cosmetics containing: fruit acids, zinc, ceramides, retinol 
  • Tight feelings, warm or stinging may occur but this is normal (due to vitamin C and lactic acid content in products)
  • Shake Atelowater vigorously before use to mix ingredients.

Additional features 

  1. Improvement in skin’s moisture and firmness
  2. Delay in the natural ageing process
  3. Visible improvement in skin cohesiveness 
  4. Smoothing and lightening of scars and stretch marks 
  5. Strengthening of flabby skin (also on the thighs, buttocks, breasts) 
  6. Regeneration of hair and nails

***

A Few bits about the collagen discovery

Collagen extracted from the fish skin is, without a doubt, a great discovery of Polish science, unfolding over the course of several years. That was not a discovery made by one specific person but it was the perfected work of a team. There would be no collagen if not for the work of the Polish School of Biochemistry.

In the 1970s Polish science shone in the field of extracting protein from marine organisms. Poland was one of the few countries to have a unit fully dedicated to marine research.

Collagen was first extracted in the 1980s but it attracted no capital support. The first “collagen patent”- no. 167114 was never to be exploited commercially until its protected legal status expired. The inventors at this time lacked two elements: an ideal fish species as a source and a perfected final filtration stage.

This was finally achieved by Professor Jozef Przybylski of the Chemistry Institute at the University of Gdansk, by using salmon as a source and silk fibers as a filter. His crowning achievement was the first Polish fish collagen able to be extracted commercially and he proved that the protein (collagen) commonly added at that times to the cosmetics was not the same as human collagen at all. Despite a number of similarities the collagen was still a biologically inactive alien body, more a form of gelatin simply working as a placebo, while collagen obtained through his method (Przybylski method) retained its crystal structure of amino acids which is identical to the human so called “triple helix” , means perfectly compatible to that of human’s.The world of science was stirred because of the Polish discovery. Opinions about the Poles having obtained the key to the youth potion emerged.

After discovery…

Collagen retaining the triple helix was a sensation but only in the sphere of specialists. In Poland it got so little publicity that by the year 2001 nobody invested in the practical utilization of the invention, despite it opening a new era in cosmetology by the fact that it was the first one that fought with the causes of skin ageing and not only with the effects.  At the turn of the century the stir around this subject slowly stopped. Native critics stated that the idea of the protein successfully reaching the deep skin through its application on the epidermis was a medical heresy. But for the marketing people who already knew that the product worked the only problem was its perish ability at high temperatures.

Collagen temperature – what’s the problem?

It seems that the market success of Polish fish collagen will not be decided by ideological certainty, but by something far more prosaic – the products resistance to temperature.

Temperature problem was crucial for the pharmaceutical and cosmetic companies who wished to obtain exclusive rights to the first medicine in the world that possessed skin -repair properties. Nevertheless , they were not seriously interested in it as long as it was prone to go through the process in which the structure of the protein changed irreversibly losing the triple helix at room temperature.

Fish collagen is a hydrate ,a concoction of proteins, which keeps its gelatinous consistency and its biological activity up to a certain temperature. The limit of this is based on its degree of hydration, on cross-linking and above all else, on the temperature at which the fish (our collagen “donors”) were raised.

Human collagen “leaves” its interspiral relationship at a temperature of 107.6F (42C) and then it dies along with the rest of the organism. Fish collagen differs from the human one only slightly. One of the differences lies in resistance to temperature…

Fish vertebrates of seasonal waters align the temperature of their organisms to the environment. The competitive battleground among Polish producers has focused on temperature resilience in the hydrates they produce, as this is the criteria determined by demand in countries with the greatest potential – that is… countries where it is hot not only in the summer. Inevitably the global success of this sensational product will rely not on quality certificates or sensational clinical research, but rather on the possibility of guaranteeing a storage temperature to the end users in their home environment.

Links:

  1. An Estimation of the Biological Properties of Fish Collagen in an Experimental In Vitro Study
  2. Multifunctional and biomimetic fish collagen/bioactive glass nanofibers: fabrication, antibacterial activity and inducing skin regeneration in vitro and in vivo
  3. The Effect of Silver Carp Skin-Derived Peptides on the Activities of VEGF and Hsp70.1 Gene Transcription Promoters
  4. Identification of Small Peptides of Acidic Collagen Extracts from Silver Carp Skin and Their Therapeutic Relevance