Why did Colway offer consumers its own vitamin C, when close to 8,000 different products with this same name have been launched into markets in Europe alone?
In present times can one develop a unique product in such a tightly saturated niche market?
It turned out to be possible.
Close to 96% of the items purchased by consumers around the world, is usually synthesised in Chinese factories with American right-handed dextrose, crystalline ascorbic acid. A form, which for a million years was unknown to our bodies, and therefore, it poorly absorbs it. The further 3% is a mixture of the former with vitamin C extracted from biomass. Only a faint percentage constitute pure plant preparations. And then, however, the bioavailability of vitamin C in these products varies considerably.
The best form of vitamin C, which contain plant growth stems, are very rare on the market, as it is not a profitable business.
Vitamin C supplementation C-olway is obtained from fruit, skin, albino and young leaves of bitter orange and buckwheat sprouts.
It does not contain fillers and additives of ascorbic acid or its derivatives. It is bio-organic, levorotatory and avant-garde. Supplements based on these herbal ingredients are only just gaining demand from consumers.
Vitamin C is the most important vitamin for the functioning of our body. Colway is a publisher of the broadest literature so far describing it in popular scientific publications. Foremost among hundreds of its biological functions seems to be conditioning of collagen biosynthesis – the process by which our connective tissue is formed.
Vitamin C-olway stormed into a group of products recognized as the best in this group of supplements in Europe. It has become one of our best sellers.
Vitamin C accumulates in the central nervous system, with neurons of the brain having especially high levels ( link).
Vitamin C in the Brain
- Most concentrated in the cerebral cortex, hippocampus, and amygdala
- Cofactor in the synthesis of the neurotransmitters
- Helps convert norepinephrine from dopamine in brain cells
- Modulates release and reuptake of neurotransmitters
- Prevents neuronal overstimulation by glutamate
- Helps maintain vascular function
Dementia is a broad term used to describe symptoms of poor thinking and memory. It affects over 35 million people worldwide and typically occurs among older adults ( link ). Studies suggest that oxidative stress and inflammation near the brain, spine and nerves (altogether known as the central nervous system) can increase the risk of dementia ( link ).
Moreover, several studies have shown that people with dementia may have lower levels of vitamin C in the blood ( link 1 ) , ( link 2 ). Furthermore, high vitamin C intakes from food or supplements have been shown to have a protective effect on thinking and memory with age (link1), (link2),(link3). In addition to its well-known antioxidant functions, vitamin C has a number of non-antioxidant functions. For instance, the vitamin is required for the enzymatic reaction hat synthesizes the neurotransmitter norepinephrine from dopamine.
Another non-antioxidant action of vitamin C in the brain is in the reduction of metal (e.g., iron, copper) ions ( link ). Further, vitamin C may also be able to regenerate vitamin E ( link ), an important lipid-soluble antioxidant. Vit C deficiency causes oxidative damage to macromolecules (lipids, proteins) in the brain ( link ). Severe vit C deficiency, called scurvy, is a potentially fatal disease. However, in scurvy, vitamin C is retained by the brain for neuronal function, and eventual death from the disease is more likely due to lack of vit C for collagen synthesis ( link ). Collagen is an important structural component of blood vessels, tendons, ligaments, and bone.
Vitamin C may help reduce the risk of anemia among people prone to iron deficiency. In one study, 65 children with mild iron deficiency anemia were given a vit C supplement. Researchers found that the supplement alone helped control their anemia ( link ).
Vitamin C content in human organs (in mg/kg)
- cheeks and facial skin – 150
- brain – 150
- pituitary glands: 400-500 (227-284mM/100g)
- eye lens: 250-310
- the adrenal glands – 400
- pancreas: 100-150
- cardiac muscle – 50
- lungs – 70
- liver – 50
- kidney: 5-150
- spleen: 100-150
- plasma – 10
- leukocytes – 350
Vitamin C (ascorbic acid) Recommended intake
Recommendations for vitamin C intake have been set by various national agencies:
- 40 milligrams per day or 280 milligrams per week taken all at once: the United Kingdom’s Food Standards Agency[link]
- 40 milligrams per day as per the recommendations of India’s National Institute of Nutrition, Hyderabad[link]
- 45 milligrams per day 300 milligrams per week: the World Health Organization[link]
- 80 milligrams per day: the European Commission‘s Council on nutrition labeling[link]
- 90 mg/day (males) and 75 mg/day (females): Health Canada 2007[link]
- 90 mg/day (males) and 75 mg/day (females): United States’ National Academy of Sciences.[link]
- 100 milligrams per day: Japan’s National Institute of Health and Nutrition.[link]
|United States vitamin C recommendations[link]|
|Recommended Dietary Allowance (adult male)||90 mg per day|
|Recommended Dietary Allowance (adult female)||75 mg per day|
|Recommended Dietary Allowance (pregnancy)||85 mg per day|
|Recommended Dietary Allowance (lactation)||120 mg per day|
|Tolerable Upper Intake Level (adult male)||2,000 mg per day|
|Tolerable Upper Intake Level (adult female)||2,000 mg per day|
Vitamin C (ascorbic acid) in New Zealand
The New Zealand Nutrition Foundation is a professional, non-profit organisation whose members believe all New Zealanders should have access to accurate information to enable them to make informed choices about food and the effect it has on their health. We help New Zealanders make these choices by providing a balanced viewpoint on important issues around food, nutrition and health.
Ministry of Health – Manatū Hauora | The Ministry works across the health sector to deliver better health outcomes for New Zealanders.
Vitamin C (ascorbic acid) in USA
LINUS PAULING INSTITUTE Micronutrient Information Center
The Linus Pauling Institute’s Micronutrient Information Center (MIC) is a source for scientifically accurate information on the functions and health effects of all micronutrients (vitamins and nutritionally essential minerals)
Vitamin C (Ascorbic acid) [University of Maryland Medical Center (UMMC) ]
Vitamin C Dosage in Disease Cathcart’s Bowel Tolerance
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans (The American Journal of Clinical Nutrition)
Vitamin C status and mortality in US adults (The American Journal of Clinical Nutrition)
Using Vitamin C to boost radiation therapy (Malaghan Institute of Medical Research, Wellington,NZ)
Vitamin C may enhance radiation therapy for aggressive brain tumours (University of Otago, Dunedin, NZ)