Native Collagen Gel

Collagen – the Foundation of Youthful Skin

Often referred to as the “protein of youth,” collagen makes up over 30% of the body’s total protein mass and an impressive 70% of the skin’s structural proteins.

Within the dermis, collagen and elastin intertwine to create a resilient, flexible network that provides skin with its firmness, elasticity, and the ability to retain essential moisture and lipophilic substances. Beyond supporting the skin, collagen is fundamental to the health and integrity of connective tissues – essentially reflecting the vitality and strength of the entire body.

For clinic use

Collagen Gel is perfect to enhance benefits of: 

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The Polish Discovery That Revolutionized Skincare

The extraction of collagen from fish skin stands as a remarkable achievement of Polish science – an innovation perfected over years of dedicated research by an entire team rather than a single inventor. This breakthrough would not have been possible without the foundational work of the Polish School of Biochemistry, whose efforts paved the way for this extraordinary advancement.

In the 1970s, Polish scientists gained international recognition for their pioneering research on marine proteins, establishing Poland as one of the few nations with a specialized marine research division.
Although the first successful extraction of collagen occurred in the 1980s, the technology initially failed to attract commercial interest. The first Polish “collagen patent” (no. 167114) remained unused until its expiration, primarily because two critical elements were still missing: the ideal fish species and a perfected final filtration technique.

The turning point came with Professor Józef Przybylski of the University of Gdańsk’s Institute of Chemistry. By utilizing salmon as the collagen source and silk fibers for final filtration, he created the first biologically active fish collagen suitable for commercial use. His work demonstrated a groundbreaking truth: collagen proteins commonly added to cosmetics at the time were little more than modified gelatins – biologically inert and ineffective compared to human collagen. In contrast, Przybylski’s method preserved the natural triple-helix structure of amino acids, making the extracted collagen nearly identical and fully compatible with that found in human skin.

The international scientific community took notice. Poland’s innovation was hailed as a major step toward the elusive “fountain of youth,” unlocking new possibilities for skin regeneration and anti-aging skincare.

After discovery…

Collagen with a preserved triple helix structure was a groundbreaking scientific discovery – yet initially recognized only within specialist circles.
In Poland, it received so little publicity that by 2001, no one had ventured to invest in its practical application, despite its revolutionary potential. For the first time, a product targeted the causes of skin aging, not just its visible effects, heralding a new era in cosmetology.

As the initial excitement faded at the turn of the century, native critics dismissed the idea, claiming that delivering active proteins into the deeper layers of the skin through topical application was medical heresy. However, marketing experts—already aware of the serum’s remarkable efficacy—saw only one significant challenge: the formula’s sensitivity to high temperatures, which limited its shelf stability.

Collagen temperature – what’s the problem?

The Hidden Key to the Global Success of Polish Fish Collagen

The true determinant of Polish fish collagen’s global success may not lie in scientific breakthroughs or ideological pride, but in something far more practical: temperature resistance.

Temperature stability was the critical hurdle for pharmaceutical and cosmetic giants who initially sought exclusive rights to the world’s first biologically active collagen with skin-repairing properties. Despite its groundbreaking potential, their interest waned as long as the product remained vulnerable to irreversible protein structure changes – losing its vital triple helix – at ordinary room temperatures.

Fish collagen is a delicate hydrate: a composition of proteins held in a gelatinous, biologically active state up to a specific temperature threshold. This stability depends heavily on factors like hydration levels, molecular cross-linking, and crucially, the thermal environment in which the source fish lived.

While human collagen denatures at approximately 42°C (107.6°F) – the body’s fatal threshold – fish collagen behaves similarly, yet exhibits variations in heat resistance. Fish species from seasonal waters adapt their body temperatures to match environmental shifts, resulting in collagen that is less thermally stable compared to that of warm-blooded organisms.

Thus, the competitive edge among Polish collagen producers has focused on perfecting the thermal resilience of their hydrates. In a global market where tropical and subtropical climates dominate, ensuring that collagen remains stable without strict cold storage has become the ultimate standard for success.

Ultimately, it is not certificates or even remarkable clinical results that will dictate the global adoption of Polish fish collagen, but rather the ability to guarantee product stability in real-world, everyday conditions.

Links:

1. An Estimation of the Biological Properties of Fish Collagen in an Experimental In Vitro Study
2. Multifunctional and biomimetic fish collagen/bioactive glass nanofibers: fabrication, antibacterial activity and inducing skin regeneration in vitro and in vivo
3. The Effect of Silver Carp Skin-Derived Peptides on the Activities of VEGF and Hsp70.1 Gene Transcription Promoters
4. Identification of Small Peptides of Acidic Collagen Extracts from Silver Carp Skin and Their Therapeutic Relevance